Our difference

Different by nature

Our human placental tissue products are composed of an extracellular matrix (ECM), growth factors and living cells native to the tissue.

Retains endogenous cells across 70% of the membrane1

Features advanced processing methods that preserve the native properties and components of fresh placental membranes. Other tissue preserving methods may alter or destroy the components of fresh placental membrane.9-12

Backed by high-quality clinical evidence2-4

National Institute for Health and Care Excellence (NICE)* provides national guidance and advice to improve health and social care:

  • NICE evaluated the quality of data for dermal substitute studies that included cure rate at 12 weeks versus standard care in diabetic foot ulcers
  • GRAFIX Cryopreserved Placental Membrane had the highest overall effect and was the only dermal substitute determined to have high quality of evidence with no serious risk of bias

See the evidence


Contains all three components – including mesenchymal stem cells1

Many placental tissue products are available, but most have only growth factors and an extracellular matrix. All three native components of placental tissues, including mesenchymal stem cells, are preserved in GRAFIX PL and GRAFIX Membranes:

  • Endogenous cells are present1
  • 3D matrix remains intact1
  • Native growth factors are retained1

Skin substitute modalities*13-23

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* Examples; not intended to be all inclusive