GRAFIX PL Membrane: Retrospective study suggests clinical equivalency with GRAFIX◊ Cryopreserved Placental Membrane10
Retrospective, open-label, multi-center study on GRAFIX PL Membrane in the management of chronic wounds*
Wounds included DFUs (n=41), VLUs (n=19), surgical wounds (n=10) and other wounds (n=28)†
Patient demographics and baseline wound characteristics
|Patients with ≥ 2 comorbidities||65%|
|Wound size (mean)||13.3 cm2|
|Wound duration prior to treatment (mean)||8.7 months|
Complete wound closure: 59.2%
GRAFIX PL Membrane closure rates similar to those previously reported for GRAFIX Membrane:
- Time to closure (median): 63 days
- Number of graft applications (median): 6 grafts
Proportion of patients who achieved closure10
Median days to closure10,16
*Defined as wounds with no progression toward closure with 4 weeks of SOC or wounds in patients with significant comorbidities that put them at high risk for nonclosure.
†Other wounds include pressure ulcers, arterial wounds, chronic wounds, open hematomas, gangrenous wounds, radiation necrosis wounds, lymphedema wounds, ischemic wounds, & necrotizing fasciitis.