Clinical study

White paper: A closer look at the use of placental membranes for wound closure
Charles B. Parks, DPM, FACFAS


A growing body of research shows chronic wounds that are challenging to treat may respond well to placental tissues. There is a variety of skin substitute products available on the market but, unfortunately, the quality of most of these products is greatly reduced during the preservation process.

Thanks to the advanced preservation methods pioneered by Smith+Nephew, GRAFIX PL Membrane and GRAFIX Lyopreserved Placental Membrane and STRAVIX Cryopreserved Umbilical Tissue retain all components of fresh placental tissue, including native living cells, as well as growth factors and an intact extracellular matrix. Studies have proven that the Smith+Nephew suite of placental tissues hastens wound closure, thus improving patients’ health and quality of life.


Download white paper